The vaccine is test on 150 people who are in progressive stage of type 1 diabetes. On the 75th Scientific Sessions of the American Diabetes Association it was announced that the Food and Drugs Administration will test the vaccine.
In the USA 1.25 million people are suffered from one type diabetes and 40,000 people will be newly diagnose each year in the U.S. Today, medical experts apply this vaccine, and prove that it is safe for use. On the other side, more than 100 years is used a vaccine for tuberculosis, called “bacillus Calmette-Gueri”. This promise to reversing this disease.
In type 1 diabetes, the body does not produce insulin. The body breaks down the sugars and starches you eat into a simple sugar called glucose. The body needs to get glucose from bloodstream into the cells of the body and insulin is a hormone to enable this process.
Our body is produce T cells where insulin is being produce. The positive benefit of this vaccine is to get rid of these T-cells. For diabetes suffers, the prime problem of their body is that it not produce insulin due to the immune system destroy the cells which create insulin.
Diabetes suffers who have been injected with vaccine, is note an increase in the level of one substance. It is called tumor necrosis factor. This increased level of TNF in the system is destroyed the T-cells which interfere process of production insulin.
From practice from before, the results was surprising. The patients suffering from diabetes type one are injected with the tuberculosis vaccine of twice a month. The results are shown how insulin started to secret on its own. But, the dangerous T-cells were eliminated. The director of the “Massachusetts General Hospital” in Boston Dr. Denise Faustman, has been thrilled of obtained results.
Dr. Denise says that their mission is to make to last for more therapeutic response. They are shown a statistically considerable response to BCG in the preliminary phase of this trial. The supplements are about people who have type one diabetes for numerous years. They will work again with those suffers. This trial is not a means of prevention, but, instead, it is supposed to create a regimen that will treat even advanced disease.
In the new process for age between 18-60 they will use the same format as this one. The patients who participate in this process will be injected with the vaccine. They can inject twice in a period of one month and then once a year for a four-year time span.
According to the previous study, inefficiency of the effects of Bacillus Calmette-Guerin (BCG) on children with diabetes at the age between 5 and 18 is published in Diabetes Care Journal. The BCG vaccine does not keep the beta-cell function or increase the remission rate.